Estudio clínico

Estilo de vida y reflujo gastroesofágico

La etiología del reflujo gastroesofágico es desconocida. El objetivo de los autores fue analizar la relación entre los hábitos cotidianos y los síntomas de reflujo gastroesofágico.

Autor/a: M Nilsson, R Johnsen, W Ye, K Hveem, J Lagergren

En el artículo titulado "Lifestyle related risk factors in the aetiology of gastrooesophageal reflux", publicado en el número de diciembre de la revista "Gut", los autores concluyen que las personas que consumen cantidades elevadas de sal presentan un mayor riesgo de reflujo gastroesofágico.

Los investigadores del Instituto Karolinska de Estocolmo (Suecia), añaden que, al contrario de lo que se pensaba, el alcohol y el té no parecen incrementar el riesgo.

La investigación se realizó sobre una muestra de 3.153 individuos con síntomas de reflujo y 40.210 sin síntomas.

Los resultados muestran que el riesgo de reflujo gastroesofágico aumenta con el número de años que hace que la persona fuma, de modo que el incremento es de un 20% entre aquellas que llevan fumando entre 1 y 5 años respecto a las no fumadoras. El consumo elevado de sal también aumenta el riesgo, de modo que las personas que suelen añadir más sal a los alimentos presentan un riesgo un 70% superior.

A continuación el abstract original del artículo:

Background/Aim: The aetiology of gastro-oesophageal reflux is largely unknown. The authors’ aim was to examine the relation between lifestyle habits and gastro-oesophageal reflux symptoms.
Subjects: Participants of two consecutive public health surveys in Nord-Trondelag, Norway.
Methods: In a case control study within the two public health surveys, 3.153 individuals who in the second survey reported severe heartburn or regurgitation during the last 12 months were defined as cases, while
40.210 people without reflux symptoms constituted the control group. The risk of reflux symptoms was estimated and multivariately calculated as odds ratios in relation to exposure to tobacco smoking, alcohol,
coffee, tea, table salt, cereal fibres, and physical exercise.
Results: There was a significant dose response association between tobacco smoking and reflux symptoms. Among people who had smoked daily for more than 20 years the odds ratio was 1.7 (95% confidence interval 1.5 to 1.9) compared with non-smokers. A similar positive association was found for table salt intake. The odds ratio for reflux was 1.7 (95% CI 1.4 to 2.0) among those who always used extra table salt compared with those who never did so. We found moderately strong negative associations between the risk of reflux and exposure to coffee, bread high in dietary fibre content, and frequent physical exercise. Intake of alcohol or tea did not affect the risk of reflux.
Conclusions: Tobacco smoking and table salt intake seem to be risk factors for gastro-oesophageal reflux symptoms. Dietary fibres and physical exercise may protect against reflux. Alcohol, coffee, and tea do not seem to be risk factors for reflux.

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